Drug Delivery to Tumors, 2024 Recent Strategies and Techniques

This book summarizes emerging drug delivery strategies and new technologies for cancer treatment from the perspective of cancer pathology, including immunotherapy strategies, biomimetic drug delivery strategies, live cell drug delivery strategies, nanocrystal technology and 3D Printing technology, etc. With the development of related fields such as pharmaceutical science, materials science and nanomedicine, drug delivery systems have made significant progress in the treatment of cancer. With the in-depth study of different types of drug delivery systems, clinical transformation will be necessary. Some clinical trials have proved the obvious advantages of drug delivery vehicles in anti-cancer treatment. However, the characterization of nanomaterials, safety issues and production issues limit the application. Importantly, accurate in vitro and in vivo models are needed to predict the therapeutic effect of drug delivery systems in the clinic. The drug delivery system has been continuouslyinnovated and improved in cancer treatment, and has broad application prospects.

Cancer pathology.- Development and advantages of drug delivery systems.- Drug delivery strategies targeting tumor.- Immunotherapy nanocarrier.- Combined therapy.- Prodrug Nanocarrier.- Smart drug delivery vehicle.- Cell-derived / bionic drug delivery vehicle.- Cellular drug delivery vehicle.- Nanocrystal technology.- Drug delivery technology 3D printing.- Microneedle-based transdermal drug delivery technology.

Dr. Lesheng Teng holds an academic appointment of Professor at Jilin University. His research is focused on a highly interdisciplinary combination of nanotechnology, biomaterials, drug delivery, and immunotherapy. He has developed various nanoparticle platforms for delivery of small molecules, proteins, and nucleic acids (e.g., siRNA and mRNA). He has published over 120 peer-reviewed papers and holds over 20 patents/patent applications. Representative papers were published in Nature Biomedical Engineering, Nano Letters, Biotechnology Advances, ACS Applied Materials & Interfaces, Journal of Controlled Release, Theranostics and Nanoscale. He has also received many awards, such as excellent supervisor, and others. Dr. Teng obtained his BS degree and PhD degree from Jilin University.

 

Dr. Zhaogang Yang is an assistant professor in the Department of Radiation Oncology, UT Southwestern Medical Center. Dr. Yang received his B.S. in Pharmaceutical Sciences (2003) and M.S. in Pharmaceutics (2006) from Peking University, China. Then, he completed his M.S. in Pharmacology (2010) and Ph.D. in Pharmaceutical Sciences (2012) at the Ohio State University, USA. He served as a post doctor in Mayo Clinic in Rochester for 1 year (2013), and a research associate at the Ohio State University for 6 years (2013-2019). Dr. Yang's research interests focus on the application of nanotechnology in drug delivery, including novel nanoparticle-based cancer detection, gene delivery and cancer therapy, and nanoelectroporation in gene therapy. He has authored 4 book chapters, more than 80 peer-reviewed journal papers, 7 conference abstracts, and 2 patents. He is a consultant editor of "International Journal of Nanomedicine". In addition, he is the Guest Editor for "Current Organic Chemistry", "Dose-Response " and “Molecules” special issues.

 

Dr. Chong Li is a professor of the College of Pharmaceutical Sciences in Southwest University (Chongqi

Update readers’ insights on the development of emerging drug delivery strategies for cancer treatment Introduces the application of frontier technologies (3D printing, nanocrystal technology, etc.) on drug delivery systems Thoroughly examines the development and clinical application of different types of drug delivery systems