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Phytochemicals in Cancer Therapy and Beyond

Langue : Anglais

Coordonnateurs : Sethi Gautam, Ashrafizadeh Milad, Rabiee Navid

Résumé
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Phytochemicals in Cancer Therapy and Beyond examines the role of natural products in the treatment of diseases, especially cancer. With a strong focus on the treatment of diseases, it demonstrates the mechanisms that natural products follow in treatment. In 24 chapters, the book describes not only regular cancer treatments, challenges, and developments in cancer treatment, in particular, phytochemicals and cellular mechanisms in cancer therapy, phytochemicals and molecular pathways in cancer, and Nano-scale delivery systems for phytochemicals in cancer therapy. The book concludes with clinical applications of phytochemical therapies. This book is a valuable resource for researchers in the field of oncology, disease therapy, diabetes mellitus treatment, cellular signaling scientists, and nanomaterial engineers.

Section I: Cancer treatment and challenges 1: New developments in treatment of cancer 2: A summary of molecular pathways responsible for cancer progression 3: Challenges in treatment of cancer with conventional strategies Section II: Phytochemicals and cancer therapy 4: Phytochemicals in suppressing cancer proliferation 5: Phytochemicals in suppressing cancer metastasis 6: Phytochemicals in providing cancer therapy sensitivity Section III: Phytochemicals in the treatment of other diseases 7: Phytochemicals in treatment of Diabetes mellitus 8: Phytochemicals in treatment of neurological diseases 9: Phytochemicals in treatment of ischemic/reperfusion injury 10: Phytochemicals in treatment of infectious diseases Section IV: Phytochemicals and cellular mechanisms in cancer therapy 11: Phytochemicals in regulating glycolysis in cancer 12: Phytochemicals in regulating apoptosis in cancer 13: Phytochemicals in regulating autophagy in cancer 14: Phytochemicals in regulating EMT and MMPs in cancer Section V: Phytochemicals and molecular pathways in cancer 15: Phytochemicals in regulating STAT3 signaling in cancer 16: Phytochemicals in regulating Wnt signaling in cancer 17: Phytochemicals in regulating NF-kB signaling signaling in cancer 18: Phytochemicals in regulating PTEN/PI3K/Akt signaling in cancer 19: Phytochemicals in regulating non-coding RNAs in cancer Section VI: Nano-scale delivery systems for phytochemicals in cancer therapy 20: Polymeric nanoparticles for delivery of phytochemicals in cancer therapy 21: Lipid-based nanoparticles for delivery of phytochemicals in cancer therapy 22: Carbon- and metal-based nanomaterials for delivery of phytochemicals in cancer therapy Section VII: Clinical applications 23: Application of phytochemicals in clinical trials for treatment of diseases and malignant tumors 24: The market of natural products around the world

Dr. Gautam Sethi is a tenured Associate Professor in Department of Pharmacology, Yong Loo Lin School of Medicine, National University of Singapore. The focus of his research over the past few years has been to elucidate the mechanism (s) of activation of oncogenic transcription factors by carcinogens and inflammatory agents and the identification of novel inhibitors of these proteins for prevention of and therapy for cancer. The findings of his research work have so far resulted in more than three hundred and fifty scientific publications in high impact factor peer reviewed journals (with h index = 109) and several international awards. He also serves as an editorial board member for over more than 15 international journals
Dr Milad Ashrafizadeh is a researcher in Sabanci university, Turkey and obtained his degree in field of Veterinary Medicine in 2020. He is an invited scholar in University of Electronic Science & Technology of China. Currently, Milad is an Editorial Board in journal of nanostructure in chemistry (IF= 6.39) and is a review editor in Frontiers journals. He has published review and research articles in international and famous journals in world. Milad has also 4 book chapters. He has published articles in high quality journals including Nanotoday, Coordination Chemistry Reviews, Advanced Science, Carbohydrate Polymers, Journal of Controlled Release and Advances in Colloid and Interface Science, among others. His interests include nanomedicine, application of nanoparticles for drug and gene delivery, targeted cancer therapy, non-coding RNAs in cancer and development of biosensors.
Navid Rabiee works in the Department of Materials Science at Pohang University of Science and Technology, South Korea.

Evaluates the role of natural products in the treatment of diseases, especially cancer
Provides details evaluating the role of natural products in regulating cellular and molecular mechanisms in cancer therapy
Focuses on the use of nanoparticles for delivery of natural products in disease therapy
Encompasses a high number of schematic figures to make it easier for readers to understand concepts
Demonstrates the mechanisms that natural products follow in treatment of diseases, especially cancer therapy