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Natural Product Based Drug Discovery Against Human Parasites, 1st ed. 2023 Opportunities and Challenges

Langue : Anglais

Coordonnateurs : Singh Archana, Rathi Brijesh, Verma Anita K., Singh Indrakant K.

Couverture de l’ouvrage Natural Product Based Drug Discovery Against Human Parasites
This book comprehensively reviews current and novel treatment strategies against human parasites, including protozoans and helminths, using natural products. The initial chapters summarize the conventional treatment strategies and natural-product based therapeutics against these parasites. It discusses biochemical tools and techniques for the discovery of natural product based drugs against human parasites. The book also covers the ingenious and innovative mechanisms to achieve drug resistance by the protozoan parasites and strategies to overcome the resistance. It entails mechanistic insight into the modulation of host immune responses to delay or inhibit parasite clearance and explores host-pathogen interactions that mediate immunity against subsequent parasite challenge. In turn, the volume helps in understanding the immunobiology of the parasites and tools to identify candidate vaccine antigens and novel delivery systems against the protozoan parasites. Lastly, it explores the role of advanced methods, including nanotechnology, marine bioprospecting, and microorganisms-derived biochemicals against the protozoan parasites.

This book is useful for students and researchers of pharmacology, parasitology, zoology and other allied fields.
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Dr. Archana Singh

Dr. Archana Singh, Assistant Professor, Hansraj College, University of Delhi, is a Ph. D. from National Institute of Plant Genome Research, Arunaasaf, Ali Marg, New Delhi. Dr. Singh is a recipient of “Young Scientist fellowship” (2012) and “Early Career Research Award” (2017) from SERB, DST, Government of India; Raman Post-Doctoral fellowship from University Grant Commission and European Molecular Biology Organization fellowship from Heidelberg, Germany.  Dr. Archana has worked as a visiting scientist at Max Planck Institute of Chemical Ecology, Jena, Germany during 2019-20 and at University of Kentucky, Lexington, USA (2016-17). Dr. Archana has been bestowed with Best Researcher Award, 2017 and Best Teacher Award, 2018. Dr. Singh has published many research articles in Journals of National and International repute such as International Journal of Biological Macromolecules, BBA Molecular Basis of Disease, Clinica Chimica Acta, Scientific Reports, Computational Biology and Chemistry, Bioorganic & Medicinal Chemistry, Anti-Cancer Agents in Medicinal Chemistry etc. Dr. Singh has also filed a patent on diagnosis of Mycobacterium tuberculosis. Dr. Archana hasalso edited two books and authored many book chapters published by Springer and Elsevier. Dr. Archana is a life-member/member of IBS, and AIMI. Besides, she has served as a reviewer for several international and national journals and book proposals. Dr. Singh has trained many post-graduate and graduate students, and currently supervises two doctoral and one post-doctoral researchers. Currently, she is working on “Plant Immunity and Human Health” with special emphasis on drug discovery for cancer, tuberculosis, parasitic diseases of human and allergens of plant origin.

Dr. Brijesh Rathi obtained Ph.D. degree in Chemistry from University of Delhi and currently, working

Reviews current and novel natural products against protozoan and helminths parasites

Discusses mechanism and strategies to overcome drug-resistance by these parasites

Summarizes tools to identify vaccine candidate against protozoan parasites

Date de parution :

Ouvrage de 596 p.

15.5x23.5 cm

Disponible chez l'éditeur (délai d'approvisionnement : 15 jours).

Prix indicatif 263,74 €

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