Metabolomics for Personalized Vaccinology Developments in Applied Microbiology and Biotechnology Series

Metabolomics for Personalized Vaccinology explores the development of personalized vaccine which requires in-depth knowledge of the patient?s health status, particularly the immune system and on metabolomics, the closest indicator of the disease phenotype. The metabolic pathway of the host's system is altered by vaccine administration. As a result, Metabolomics for Personalized Vaccinology provides understanding of how metabolomics might be employed in personalized vaccinology. Over the last few years, researchers have published articles on personalized vaccine, but these are sparse. Therefore, compiling this information will help the reader to get an overview of the progress of this field, despite its being at its infancy. Metabolomics for Personalized Vaccinology is ideally suited for researchers and postgraduate students who are interested in clinical and non-clinical studies where metabolites are used for identification of disease and therapeutic targets.

1. Personalized Vaccinology 2. Vaccine Adjuvants and their role in modulating immune signaling pathways 3. Technologies to measure vaccine immune response against infectious diseases 4. Vaccines for Cancer 5. Vaccines for Autoimmune Diseases 6. Vaccines for Allergy 7. Virus vaccine production using cell-based technology 8. Dendritic cell-based cancer vaccine production

Dr. Mahbuba Rahman earned her B.Sc. (Honors), M.Sc in Microbiology and an M.S. in Environmental Science. She completed her PhD in Metabolic Engineering from the Department of Bioscience and Bioinformatics, Kyushu Institute of Technology, Japan. Post Ph.D., she worked with a transgenic mice model of Smith–Lemli–Opitz syndrome, which is an inborn error of cholesterol synthesis, at Children’s Hospital Research Institute (CHORI), Oakland, California. Mahbuba has published several research articles including clinical and non-clinical research in high-impact factor journals. She also authored multiple review articles and book chapters in high-impact journals and with well-known publishers. She is also an editor of an eBook on cancer immunotherapy and an editor of a hard copy book on Metabolomics A Path Towards Personalized Medicine. She is also a special topic editor and guest editor in Frontiers in Genetics, Frontiers in Immunology, and in Journal of Microbiological Methods. At present, she is an Adjunct Assistant Professor at the Department of Biology, at McMaster University. She is investigating the role of global regulators in pathogenic and non-pathogenic microorganisms using systems biology approaches.

• Gives insight in the importance of personalized vaccines in clinical and research environment
• Provides the principles of metabolomics and integration of other systems biology approach for personalized vaccine development
• Discusses vaccine manufacturing technologies and importance of metabolomics for personalized vaccine development
• Discusses the scope of personalized vaccine in relation to specific diseases.
• Possible scope of metabolomics in biomarker identification and vaccine discovery