Epitope mapping (practical approach ser. 248) A Practical Approach Practical Approach Series Series, Vol. 248

An epitope is a structural region of an antigen that is recognized by an antibody and is therefore central to the immune response. This book describes the various methods for their location and characterization. This process is an essential part of developing non-pathogenic vaccines.

Introduction to epitope mapping, Synthetic peptides. Part 1: pepscan assay to define antigenic determinants for antibodies .B cell Epitopes), Delineation of helper T cell epitopes and MHC, Combined T and B cell epitopes, Cytotoxic T cell eptitopes, Peptide mimic libraries, Steric competition mapping, Oligosaccharide libraries, Phage display libraries, Site-directed mutagenesis