Cancer Epigenetics and Nanomedicine Targeting the Right Player via Nanotechnology

Overview of Cancer, Internal and External Factors Associated with Cancer 1. Overview of Cancer: Mechanism of Carcinogenesis Uttara Saran and Chitra Thakur 2. Tumor metabolism and micro-nutrients: New insights to target malignant tumors Santhi Latha Pandrangi, Sireesha V. Garimella, and Prasanthi Chittineedi 3. Inflammation and cancer: An insight Suchandrima Saha, Monisankar Ghosh 4. Environmental Causes of Cancer Priya Wadgaonkar 5. Cancer stem cells: challenges for cancer therapies Rashi Arora and Apoorva Uboveja 6. Carving a therapeutic niche for metastatic cancer: opportunities and challenges Sireesha V. Garimella Epigenetics and its Importance in Cancer Therapies 7. An overview on the epigenetics and cancer Rajendra Prasad Pangeni 8. Causes and Consequences of Variable Tumor Microenvironment on Tumor Evolution Jowana Obeid and Mehdi Damaghi 9. Understanding epigenetics in cancer stem cells and chemoresistance Prajakta Oak and Chitra Thakur 10. Cancer Biomarkers: Where Genetics Meets Epigenetics Snehal Nirgude, Jennifer M. Kalish 11. Epigenetics Approach in Cancer Treatment with Focus on Lung and Breast Cancer Sayani Bhattacharjee 12. Epigenetic diets and drugs in cancer prevention and treatment Chitra Thakur and Uttara Saran Nanomedicine Targeting Epigenetic Machinery in Cancer Therapy 13. Nanotechnology and its relevance in cancer therapies Nur Khatijah Mohd Zin 14 Epigenetic modulation by biosynthetic nanomaterials from plants in cancer Ritu Karwasra 15 Nanotechnology augmented Immunotherapy for cancer Akshata R. Naik 16 Nanoparticles in metastatic cancer treatment Prashant Kesharwani 17 Amine-terminated dendrimers: A novel method for diagnose, control and treatment of cancer Somaye Akbari, Yeganeh Modirrousta 18. Nanomedicine and Epigenome: possible health risks, benefits, and future Nitin Verma 29. Smart Cancer Nanomedicine: Challenges and Future Opportunities Moumita Roy

Dr. Prashant Kesharwani is working as an assistant professor of pharmaceutics at the School of Pharmaceutical Education and Research, Jamia Hamdard University, New Delhi, India. He has more than 12 years of teaching, research, and industrial experience at international levels from various countries, including the United States, Malaysia, and India. An overarching goal of his current research is the development of nanoengineered drug delivery systems for various diseases. He has more than 300 international publications in well-reputed journals and more than 20 international books (Elsevier). He is a recipient of many research grants from various funding bodies. He is also a receipt of several internationally acclaimed awards such as the most prestigious “Ramanujan Fellowship Award” from the Science and Engineering Research Board, Government of India. He actively participates in outreach and scientific dissemination for the service of the wider community.

Dr. Thakur has expertise in molecular oncology and has been working in the areas of environmental carcinogenesis, mouse models of human cancers, epigenetics, and the molecular mechanisms implicated in human lung and breast cancers. She sits on the editorial board of several scientific journals and is actively involved in the editorial peer-review process and policymaking. She has published outstanding research articles (~40) in mainstream cancer journals such as the “Signal Transduction and Targeted Therapy”, “Frontiers in Oncology”, “Seminars in Cancer Biology” and “Cancer Letters” etc. and have made significant contributions towards the discovery of signal transduction pathways, chemotherapeutic drug resistance implicated in human lung and breast cancers, cancer epigenetics and cancer metabolism. She is a recipient of several internationally acclaimed awards such as “DFG German Excellence Initiative Award, 2007”, “NIH-Big Data Training for Translational Omics Research, for Travel and participation a

• Delivers a detailed and a complete journey of how cancer develops, its genetics as well as other internal and external factors that are contributors of carcinogenesis.
• Provides an in-depth knowledge on epigenetics and the various epigenetic biomolecules, enzymes and other signaling pathways that are the promising entities for drug discovery and chemotherapeutics.
• Presents state-of-the-art information on the next generation cancer therapies, challenges, and future of the field.