Annual review of genomics and human genetics 2000 Volume 1

Genetics, biology, and disease. Two centuries of genetics. Gene family evolution and homology : genomics meets phylogenetics. Iron metabolism : iron deficiency and iron overload. How many genes can make a cell. The human major histocompatibility complex. Genetic screening of newborns. From the sarcomere to the nucleus. Estimating allele age. Bioinformatics tools for whole genomes. Trinucleotide repeats. Sequence variation in genes and genomic DNA. Genetic perspectives on human origins and differentiation. Patterns of genetic variation in Mendelian and complex traits. DNA helicases, genomic instability and human genetic. Williams syndrome and related disorders. Public concern about genetics. Apolipoprotein E. Methods to detect selection in populations with applications to the human.