The Human Brain during the Second Trimester 190– to 210–mm Crown-Rump Lengths Atlas of Human Central Nervous System Development, Volume 10

This tenth of 15 short atlases reimagines the classic 5-volume Atlas of Human Central Nervous System Development. This volume presents serial sections from specimens between 190 mm and 210 mm with detailed annotations. An introduction summarizes human CNS developmental highlights around 5 months of gestation. The Glossary (available separately) gives definitions for all the terms used in this volume and all the others in the Atlas.

Features

• Classic anatomical atlas
• Detailed labeling of structures in the developing brain offers updated terminology and the identification of unique developmental features, such as germinal matrices of specific neuronal populations and migratory streams of young neurons
• Appeals to neuroanatomists, developmental biologists, and clinical practitioners
• A valuable reference work on brain development that will be relevant for decades

CONTENTS

PART I. INTRODUCTION --------------------------------------------------------------------------------------------1

Specimens and Organization --------------------------------------------------------------------------------1

Developmental Highlights -----------------------------------------------------------------------------------1

References ------------------------------------------------------------------------------------------------------5

PART II. 170 mm Crown-Rump Length, Y197-65, Horizontal ---------------------------------------------------4

Low-Magnification Plates 1–8 A–B ----------------------------------------------------------------------6-23

High-Magnification Plates 9-23--------------------------------------------------------------------------24-53

PART III. 205 mm Crown-Rump Length, Y24-60, Sagittal ------------------------------------------------------56

Low-Magnification Plates 24-28 A–B -----------------------------------------------------------------58-65

Cerebral Cortex Plates 29-30-----------------------------------------------------------------------------66-67

PART IV. 210 mm Crown-Rump Length, Y94-62, Frontal -----------------------------------------------------68

Low-Magnification Plates 31–45 A–B -----------------------------------------------------------------69-99

High-Magnification Plates 46-58 A–B---------------------------------------------------------------100-125

Cerebral Cortex Plates 59-62--------------------------------------------------------------------------126-129

Shirley A. Bayer received her PhD from Purdue University in 1974 and spent most of her scientific career working with Joseph Altman. She was a Professor of Biology at Indiana-Purdue University in Indianpolis for several years, where she taught courses in Human Anatomy and Developmental Neurobiology while continuing to do research in brain development. Her lengthy publication record of dozens of peer reviewed scientific journal articles extends back to the mid 1970's. She has co-authored several books and many articles with her late spouse, Joseph Altman. It was her research (published in Science in 1982) that proved that new neurons are added to granule cells in the dentate gyrus during adult life, a unique neuronal population that grows. That paper stimulated interest in the dormant field of adult neurogenesis.

Joseph Altman, now deceased, was born in Hungary and migrated with his family via Germany and Australia to the United States. In New York, he became a graduate student in psychology in the laboratory of Hans-Lukas Teuber, earning a PhD. in 1959 from New York University. He was a postdoctoral fellow at Columbia University, and later joined the faculty at the Massachusetts Institute of Technology. In 1968, he accepted a position as a Professor of Biology at Purdue University. During his career, he collaborated closely with Shirley A. Bayer. From the early 1960s to 2016. He published many articles in peer-reviewed journals, books, monographs, and online free books that emphasized developmental processes in brain anatomy and function. His most important discovery was adult neurogenesis, the creation of new neurons in the adult brain. This discovery was made in the early 1960s while he was based at MIT and was largely ignored in favor of the prevailing dogma that neurogenesis is limited to prenatal development. After Shirley’s paper proved that new neurons are adding to granule cells in the hippocampus, Altman’s