Integrated Nano-Biomechanics Micro and Nano Technologies Series

Integrated Nano-Biomechanics provides an integrated look into the rapidly evolving field of nanobiomechanics. The book demystifies the processes in living organisms at the micro- and nano-scale through mechanics, using theoretical, computational and experimental means. The book develops the concept of integrating different technologies along the hierarchical structure of biological systems and clarifies biomechanical interactions among different levels for the analysis of multi-scale pathophysiological phenomena. With a focus on nano-scale processes and biomedical applications, it is shown how knowledge obtained can be utilized in a range of areas, including diagnosis and treatment of various human diseases and alternative energy production.

This book is based on collaboration of researchers from a unique combination of fields, including biomechanics, computational mechanics, GPU application, electron microscopy, biology of motile micro-organisms, entomological mechanics and clinical medicine. The book will be of great interest to scientists and researchers involved in disciplines, such as micro- and nano-engineering, bionanotechnology, biomedical engineering, micro- and nano-scale fluid-mechanics (such as in MEMS devices), nanomedicine and microbiology, as well as industries such as optical devices, computer simulation, plant based energy sources and clinical diagnosis of the gastric diseases.

Section 1: Introduction to nano-biomechanics

T. Yamaguchi

Section 2: Biomechanics of microcirculation

Chapter 2.1 Behavior of capsules in flow

S. Nix

Chapter 2.2 Behavior of red blood cells

T. Omori

Chapter 2.3 Adhesion of cells

Y. Imai

Chapter 2.4 Formation and destruction of the primary thrombus

H. Kamada

Section 3: Biomechanics of digestive systems

Chapter 3.1 Dynamics of swallowing

Y. Imai

Chapter 3.2 Mixing in stomach

Y. Imai

Chapter 3.3 Transport phenomena of gut flora

T. Ishikawa

Section 4: Biomechanics for pathology and treatment

Chapter 4.1 Development of cerebral aneurysms

Y. Shimogonya

Chapter 4.2 Electroporation for cancer treatment

N. Matsuki

Chapter 4.3 Microbubbles for blood transfusion

N. Matsuki

Chapter 4.4 Percutaneous absorption of medicine

K. Kikuchi

Section 5: Ciliary motion

Chapter 5.1 Ciliary structure

H. Ueno

Chapter 5.2 Motor proteins of cilia

H. Ueno

Chapter 5.3 Computational modeling of ciliary motion

T. Omori

Section 6: Swimming microorganisms

Chapter 6.1 Swimming of a solitary cell

Y. Shimogonya

Chapter 6.2 Suspension of swimming cells

T. Ishikawa

Chapter 6.3 Bioconvection generated by microalgae

A. Kage

Section 7: Microfluidic devices based on biomechanics

Chapter 7.1 Measurement techniques of cellular flow

R. Lima

Chapter 7.2 Controlling cell-free layer

M. Saadatmand

Chapter 7.3 Separation of motile bacteria

T. Ishikawa

Section 8: Biomimetics

Chapter 8.1 - Design of fish fin

K. Kikuchi

Chapter 8.2 - Bloodsucking of mosquito

K. Kikuchi

Chapter 8.3 - Virtual chameleon

F.Mizuno

Academics and scientists in micro- and nanotechnology, nanoengineering/-fabrication, biotechnology, biomedical engineering,microbiology and nanomedicine. Also researchers and R&D engineers in industries such as pharmaceutics, optical devices, MEMS devices, computer simulation, plant based energy sources, clinical diagnosis and therapeutics.

• Provides knowledge of integrated biomechanics, focusing on nano-scale, in this rapidly growing research field
• Explains how the different technologies can be integrated and applied in a variety of biomedical application fields, as well as for alternative energy sources
• Uses a collaborative, multidisciplinary approach to provide a comprehensive coverage of nano-biomechanics