Infection and Autoimmunity (3^rd Ed.)

In 2020 we lost Noel Rose, co-editor of the classic Infection and Autoimmunity. To honor and respect his work, a group of experts in the field have taken the initiative to make this book perpetual.

The third edition of Infection and Autoimmunity updates all the recent and leading papers on infection and autoimmunity, in addition to a dedicated section on to the correlation between SARS-CoV-2 infection and autoimmunity. From the very beginning of the COVID-19 pandemic, numerous papers have been published, including studies conducted by the editors and authors of the book, on COVID-19 and autoimmunity, and therefore this knowledge has been incorporated into this new edition. The addition and extended coverage on SARS-CoV-2/COVID-19 and autoimmunity are pivotal for the third edition of the book due to the COVID-19 pandemic.

Medical students and practitioners, as well as academic staff in medical schools globally, are enthusiastic in searching for better understanding of the correlation between infection and autoimmunity in general, and the long-term effects of SARS-CoV-2 and COVID-19 on the immunce system in particular, especially in terms of autoimmunity related to the virus.

1. Introduction

Part 1: Mechanisms of Autoimmunity induction by infectious agents and vaccination 2. Molecular Mimicry and Autoimmunity 3. Epitope Spreading in Autoimmune Diseases 4. The immune neuroendocrine system, infections, and rheumatic diseases 5. CD5-Expressing B-1 Cells and Infection 6. Lymphocytes and Infection in Autoimmune Diseases 7. Endothelial Cell Autoreactivity and Infection 8. Microbiota and Autoimmunity 9. Infection, Autoimmunity, and Vitamin D 10. Seasonality and Autoimmunity 11. The Protective Role of Helminths in Autoimmunity 12. Vaccination and Autoimmunity 13. BCG Vaccination 14. Opportunistic Infections and Autoimmune Diseases 15. Can Antibiotics Cure Autoimmune Diseases?

Part 2: Viruses and Autoimmunity 16. Anti-Viral Therapy, Epstein–Barr Virus, Autoimmunity, and Chaos (The Butterfly Effect) 17. Roles for Cytomegalovirus in Infection, Inflammation, and Autoimmunity 18. Hepatitis C and Mixed Cryoglobulinemia: An Update 19. HIV Spectrum and Autoimmune Diseases 20. Parvovirus Infection and Its Association with Autoimmune Diseases 21. Human T-lymphotropic Virus Type 1 and Rheumatic Diseases: A Link Between Infection and Autoimmunity 22. Sjögren’s Syndrome: Role of Viruses and Viral-Like Sequences 23. Viral Infection and Heart Disease: Autoimmune Mechanisms 24. Celiac Disease and Rotavirus Infection 25. Theiler’s Murine Encephalomyelitis Virus-Induced Demyelinating Disease (TMEV-IDD) and Autoimmunity

Part 3: Bacteria and Autoimmunity 26. Rheumatic Fever: How Streptococcal Throat Infection Triggers an Autoimmune Disease 27. Helicobacter pylori Infection and Gastric Autoimmunity: Coincidence or a Cause and Effect Relationship? 28. Multiple Sclerosis and Creutzfeldt–Jakob Disease are Autoimmune Diseases Probably Caused by Exposure to the Nasal Microbe Acinetobacter 29. Infection and Autoimmunity in Antibiotic-Refractory Lyme Arthritis 30. Streptococcus Pneumoniae and Autoimmunity: A Systematic Review of the Literature: How Pneumococcal Infection Might Be Related to Rheumatic Diseases 31. Mycobacteria and Autoimmunity 32. Mycobacterium avium Subspecies Paratuberculosis and Human Disease: Bridging Infection and Autoimmunity 33. Leprosy and Autoimmunity

Part 4: Parasites and autoimmunity 34. Parasitic Infection and Autoimmunity 35. Toxoplasma and Autoimmunity 36. Malaria and Systemic Lupus Erythematosus: Complex Interactions and Reciprocal Influences

Part 5: Autoimmune diseases and infections 37. Anti-Saccharomyces cerevisiae Antibodies Autoimmune Diseases 38. The Infectious Origin of the Anti-Phospholipid Syndrome 39. Infections and Systemic Lupus Erythematosus 40. Infections and Idiopathic Inflammatory Myopathies 41. Rheumatoid Arthritis and Infections: More Than an Association? 42. Infection and Systemic Sclerosis 43. Infection and Spondyloarthropathies 44. Infection and Behçet Disease 45. Vasculitides and Hepatitis C Infection 46. The Role of Infection in Inflammatory Bowel Disease: Initiation, Exacerbation and Protection 47. Post-Infectious Arthritis and Reactive Arthritis 48. Infection and Autoimmune Liver Diseases 49. The Role of infection in Immune-mediated Thrombocytopenia 50. Viral Infections and Type 1 Diabetes 51. Infection and Autoimmune Thyroid Diseases 52. Pemphigus and Infection 53. Infections and Autoimmune Renal Diseases 54. Infections Associated with Retinal Autoimmunity 55. Oral Infections and Autoimmune Diseases 56. infection and Guillain–Barré Syndrome 57. Acute Disseminated Encephalomyelitis

Part 6: COVID-19 and autoimmunity SARS-CoV-2 (COVID-19) and Autoimmunity 58. COVID-19 and autoimmunity 59. COVID-19 and autoantibodies 60. COVID-19 and vasculitis 61. COVID-19 vaccines and autoimmunity

• Fully revised and updated by a global group of experts, dedicated to and in honor of Noel Rose
• Includes 52 completely updated chapters with the latest developments in the field
• Is the only book directed specifically at the interactions between infectious agents and autoimmunity
• Describes the prevalence and incidence of global issues and current therapeutic approaches
• Addresses in full, details of the mechanisms behind the emergence of autoimmune diseases secondary to infections
• Brings the reader up-to-date and allows easy access to individual topics in one place