Falciparum Malaria Diagnostic Tools, Therapeutic Advances, and Future Opportunities

Langue : Anglais

Coordonnateur : Qidwai Tabish

Couverture de l’ouvrage Falciparum Malaria

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Sommaire
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Falciparum Malaria: Diagnostic Tools, Therapeutic Advances, and Future Opportunities discusses the current state of therapeutic options for malaria, antimalarial drugs and drug targets. The book also covers recent progress in the development of vaccines and other approaches for malaria treatment, prevention and control and explores diagnostic tools and biomarkers. Sections examine potential biomarkers and their applications, molecular diagnostic tools, multi-omic approaches for the characterization of therapeutic action of potential new antimalarials, therapeutic advances in falciparum malaria, antimalarial drugs, targeting parasite apicoplast for antimalarial drug discovery, cellular and adjunctive therapies for malaria treatment, and future opportunities.

With contributions from experts in the field, this book is an ideal resource for academics, researchers, graduates and industry engaged in malaria research, its diagnosis, and treatment.

Part I: Diagnostics and Biomarkers in Falciparum Malaria 1. Molecular Mechanism of inflammatory signaling pathway in severe malaria pathogenesis 2. Exploration of potential biomarkers and their applications for detection of malaria 3. Laboratory diagnosis of malaria: An update 4. Molecular diagnostic tools in detection of mixed parasitic infections: Current scenario and challenges 5. Multi-omic approaches for characterisation of therapeutic action of potential new antimalarials Part II: Therapeutic Advances in Falciparum Malaria 6. Antimalarial drugs: Discovery, mechanism of action and drug resistance 7. Targeting parasite apicoplast for antimalarial drug discovery 8. Antimicrobial peptides as a new class of anti-malarial therapeutic agents 9. Investigation of RNA Interference in malaria Parasites 10. Current adjunctive therapy for the treatment of severe and cerebral malaria in humans 11. Cellular therapies for malaria treatment and reduction of malaria induced deaths in endemic regions 12. Malaria diagnostic and treatment: Future opportunities

Dr. Tabish Qidwai PhD is currently an Associate Professor and part of the Faculty of Biotechnology, IBST, Shriramswaroop Memorial University, Lucknow in India. Dr. Qidai pre-doctoral and doctoral research was at CSIR-CIMAP & UP Technical University Lucknow from 2008-2013. He studied host polymorphism in genes related to Plasmodium falciparum infection in an endemic region of India and later worked on the identification and characterization of antimalarial drug targets in Plasmodium falciparum. His postdoctoral research from 2-14-2018 at Babasaheb Bhimrao Ambedkar University, Lucknow explored compounds as potential antimalarial against Plasmodium falciparum. Dr. Qidwai has published over 30 journal articles, contributed book chapters, and recently published a book on Exploration of Host Genetic Factors associated with Malaria. He is a Life member of Society of Biological Chemists, India, the Indian Biophysical Society, and the Indian Science Congress Association. He is also a Member of the International Association of Engineers (IAENG) and the International Society for Infectious Diseases.

Reviews current therapeutic strategies of falciparum malaria
Covers antimalarial drugs, peptides, vaccines and RNAi approaches against malaria
Explores antimalarial drug targets in parasites
Discusses biomarkers and new diagnostic tools