Current Trends in the Diagnosis and Management of Metabolic Disorders

This volume provides an overview of the biochemical basis of metabolic diseases and molecular basis of chemical pathologies. Metabolic disorders occur when metabolic processes in the body are disrupted. They contribute a significant burden to human health globally. They can be congenital or acquired, for example, diabetes mellitus, obesity, metabolic syndrome, osteoporosis, osteopenia, mild-moderate hypovitaminosis D, erectile dysfunction, dyslipidemia, and thyroiditis. Metabolic disorders have gained significant importance due to the exponential increase in obesity worldwide. Early diagnosis of metabolic disorders is important in order to employ lifestyle and risk factor modification.

Features:

• An overview of the biochemical basis of metabolic diseases and molecular basis of chemical pathologies
• Describes recent trends in diagnosis of metabolic disorders
• Discusses management and treatment of metabolic diseases
• Allows quick identification and retrieval of material by researchers learning the efficacy, associated dosage and toxicity of each of the classes of compounds
• Suitable globally for graduate and postgraduate students studying metabolic diseases

1 Overview: Biochemical basis of metabolic diseases

2 Molecular basis of chemical pathologies

3 Metabolic changes and biochemical monitoring during pregnancy

4 Recent trends in the diagnosis of metabolic disorders

5 The role of mitochondrial dysfunction in metabolic syndrome

6 Artificial intelligence in metabolic disorders

7 The burden of diabetes mellitus: biochemical and nutritional aspects

8 Clinical Management of Diabetes Mellitus

9 Lipids and lipoprotein metabolism, dyslipidemias and management

10 Mineral metabolism and metabolic bone diseases

11 Biochemical basis of renal diseases

12 Clinical management of renal diseases

13 Metabolic dysregulation in cardiovascular diseases: a beat on cardiometabolic diseases

14 Consideration of the pathophysiology and treatment of Type 1 and Type 2 diabetes mellitus and other diabetes mellitus subtypes

15 Clinical management of cardiovascular diseases

16 Biochemical basis of neurological disorders

17 Clinical management of neurological disorders

18 Endothelial dysfunction and related disorders

19 Alcoholic and non-alcoholic liver diseases: biochemical aspects

20 Common pathogens involved in metabolic diseases

Seth Kwabena Amponsah (PhD) is a Senior Lecturer and Head of Department of Medical Pharmacology, University of Ghana Medical School. He has an MPhil and PhD in Pharmacology. He has had post-doctoral fellowships under BANGA-Africa Project and BSU III (DANIDA - Denmark). He has over 12 years’ experience in teaching and research. His research focus includes Clinical Pharmacology (infectious disease and antimicrobial stewardship): prudent use of antimicrobials, antimicrobial level monitoring, and efficacy of antimicrobials in patients. He also has experience in population pharmacokinetic modeling; non-compartment pharmacokinetic estimation; and pharmacokinetic evaluation of new drug formulations. He has published over 50 research articles, 1 book, 10 book chapters and several conference abstracts. He is an academic editor for PLOS One and an Associate Editor for Pan African Medical Journal.

Emmanuel Kwaku Ofori (PhD) is currently a Senior Lecturer and the Head of the Department of Chemical Pathology, University of Ghana Medical School. He earned his PhD in July 2018 from the University of Lausanne, in Switzerland. He teaches several disciplines in the health sciences (medical, nursing, veterinary, and laboratory sciences, among others). He has supervised and mentored many undergraduate and postgraduate students. His research focuses on lipidomics, metabolic medicine, and steroidal adaptations to diet and exercise. He has an overall aim of becoming an international expert on translational research into metabolic diseases. He has about 22 publications to his credit in top-ranked peer-reviewed journals. He has also presented several abstracts at international conferences.

Yashwant V. Pathak (PhD) has over 15 years of experience in an Institution of Higher education as Dean, and over 30 years as faculty and as a researcher in higher education after his PhD. He currently holds the position of Associate Dean