Comparative Mammalian Immunology The Evolution and Diversity of the Immune Systems of Mammals Developments in Immunology Series

Langue : Anglais

Auteur : Tizard Ian R

Couverture de l’ouvrage Comparative Mammalian Immunology

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Comparative Mammalian Immunology: The Evolution and Diversity of the Immune Systems of Mammals provides a review on the current knowledge of mammalian immune systems from a comparative viewpoint. This reference encompasses recent work on the immune systems of marine mammals, bats and marsupials in addition to other lesser-known species, with the immune systems of humans and laboratory mice as components of chapters on primates and rodents respectively. The book also makes use of the most recent studies on the genomic sequences of the mammals to identify both common and unique features of each mammal's immune system.

The book elucidates the complex, but coordinated and controlled series of interactions involving cells and molecules that has evolved to protect the host against disease. Mammals consist of a highly diverse group of animals in which the immune system has been subjected to a variety of selective pressures. This is reflected in differences in the organization and function of their immune systems, and is especially seen in those gene families characterized by complexity and polymorphism.

SECTION 1: MAMMALIAN IMMUNOLOGY 1. The phylogeny of the mammals 2. The evolution of viviparity 3. The evolution of lactation 4. Endothermy 5. The mammalian microbiota and its role in the evolution of the immune system 6. Innate immunity in mammals 7. The evolution of the major histocompatibility complex and kir receptors 8. The generation of b cell and t cell antigen diversity 9. Mammalian lymphoid systems 10. Mammalian longevity and aging

SECTION 2: MAMMALIAN ORDERS 11. Monotremes: Echidnas and platypus 12. Marsupials: Koalas and kangaroos 13. Placentals: Cetartiodactyla: camels and llamas 14. Cetartiodactyla: Pigs and peccaries 15. Ruminants: Cattle, and sheep 16. Cetaceans: Dolphins and whales 17. Chiropterans: Bats 18. Carnivora 19. Perissodactyls: Horses 20. Lagomorphs: Rabbits 21. Rodents: Rats and mice 22. Primates: Monkeys, apes, and humans 23. Paenungulates: Elephants and sirenians 24. Xenarthrans: Sloths and anteaters 25. Synthesis

Ian Tizard, BVMS, BSc, PhD, DSc (Hons), DACVM, is a Diplomate of the American College of Veterinary Microbiologists and a University Distinguished Professor Emeritus of Immunology, Department of Veterinary Pathobiology, The Texas Veterinary Medical Center at Texas A &M University (TAMU), College Station, Texas, USA. Dr. Tizard earned his Bachelor of Veterinary Medicine and Surgery from the University of Edinburgh, Scotland in 1965. He then completed a Bachelor of Science in Pathology and a PhD in Immunology. After completing his studies, Dr. Tizard became a Post-Doctoral Fellow at the University of Guelph, where he remained on as a professor until 1982 when he moved to TAMU. Dr. Tizard wrote the first standardized textbook on Veterinary Immunology in 1977. This text, now in its 10^th edition, is used worldwide, and has played a major role in establishing Immunology among the key disciplines of Veterinary Science.

Demonstrates multiple diverse pathways and mechanisms to optimize resistance and survival in the face of infectious diseases
Shows the clear patterns of emergence of different immunologic traits among the diverse orders of mammals
Reflects issues with innate or adaptive immune systems
Serves as a comprehensive review of the current state of knowledge of the immune system of each mammalian order