Anxiety, Gut Microbiome, and Nutraceuticals Recent Trends and Clinical Evidence Nutraceuticals Series

Healthy gut function is associated with normal central nervous system (CNS) function. Hormones, neurotransmitters, and immunological factors released from the gut are known to send signals to the brain either directly or via autonomic neurons. Recently, studies have emerged focusing on variations in the microbiome and the effect on various CNS disorders, including, but not limited to anxiety, depressive disorders, schizophrenia, and autism. Anxiety, Gut Microbiome, and Nutraceuticals: Recent Trends and Clinical Evidence is focused on understanding the role of gut microbiomes on anxiety and how it can be treated using various nutraceuticals. It covers recent trends and clinical evidence in application of nutraceuticals in treating anxiety and related disorders.

Key Features

• Explains various factors related to anxiety and anxiety-related disorders including pathophysiological and pharmacological factors
• Discusses the pharmacology behind anxiety and related disorders
• Explores the role of gut microbiota and its relationship with anxiety and related disorders
• Describes different nutraceuticals and classes of nutraceuticals which can be useful to treat anxiety and related disorders

In recent years, there has been an increased interest in nutraceuticals and their applications in treating many diseases and disorders. The market has grown tremendously, and this book focuses on the many clinical studies reporting on the usefulness of nutraceuticals in treating such health conditions.

1. Nutraceuticals and its applications –recent trends and challenges. 2. Anxiety disorders: background, anatomy and pathophysiology. 3. Diagnosis and management of anxiety disorders. 4. Anxiety disorders: Symptoms and causes. 5. Pharmacology of human anxiety. 6. Gut Microbiota and Mental Health: The Gut Brain Axis. 7. Inflammation and the gut microbiome in depression and anxiety. 8. Stress, depression, diet, and the gut microbiota: human–bacteria Interactions at the core of psychoneuroimmunology and nutrition. 9. Effects of Psychological, Environmental, and Physical Stressors on the Gut Microbiota. 10. Translating evidence to real-world reproducibility and specific evidence for Nutraceuticals. 11. Nutraceuticals as modulators of gut microbiota: Role in therapy! 12. Stress disorder and gut microbiota. 13. Polyphenolic Nutraceuticals to Combat Oxidative Stress Through. 14. The Role of Functional Foods and Nutraceuticals in Gastrointestinal Health. 15. Traditional therapy of prebiotics and probiotics as treatment for anxiety and stress. 16. Oral β-Lactamase Therapies Designed for the Prevention of Antibiotic-Induced Disruption of the Gut Microbiome. 17. Recent trends in the role of the human gut microbiome in neurological function and brain disorders. 18. Synbiotic: Traditional Approach, Present Status and Future Outlook. 19. Interplay between nutraceuticals and gut microbiota some clinical evidences. 20. Manipulation of Gut Microbiome to Improve Mental Health. 21Functional Constituents of Yacon (Smallanthus sonchifolius) for gut rejuvenation.

Sarvadaman Pathak, MD, went to University of Houston for undergraduate studies, with a concentration in Biochemistry and Pre-Medicine. Following that he pursued a Doctor of Medicine degree from Avalon University School of Medicine Summa Cum Laude. He was educated partially in Belize, Mexico with all clinical experience in Chicago, IL. After graduating from medical school, he focused on research and worked at the University of South Florida. In 2013 he completed a one-year clinical fellowship in Traditional Chinese Medicine, including Chinese herbalism, with a focus on eastern western integrative medicine at the Dalian Medical University in Dalian, Liaoning province in Mainland China. Currently he works for the Veterans Affairs and University o fSouth Florida, Internal Medicine, and focuses on cancer research and pediatrics research.

Yashwant V. Pathak, PhD, is currently the associate dean for faculty affairs at College of Pharmacy, University of South Florida, Tampa, Florida. Pathak earned his MS and PhD degrees in pharmaceutical technology from Nagpur University, Nagpur, India, and EMBA and MS degrees in conflict management from Sullivan University, Louisville, Kentucky. With extensive experience in academia and industry, Pathak has over 150 publications, research papers, abstracts, book chapters, and reviews to his credit. He has presented over 180 presentations, posters, and lectures worldwide in the field of pharmaceuticals, drug delivery systems, and other related topics. He has received several national and international awards including Fulbright Senior Scholar fellowship for Indonesia, Endeavour executive fellowship from Australian Government, CNPQ research award from Brazil Government and also was recognized by USF as outstanding faculty award and global engagement achievement award.

Con Stough, PhD, is Professor of Cognitive Neuroscience and Psychology and Director, Centre for Human Psychop