SERS for Point-of-care and Clinical Applications

SERS for Point-of-care and Clinical Applications focuses on the use of Surface-Enhanced Raman Spectroscopy (also known as Surface-Enhanced Raman Scattering) techniques in clinical and point-of-care settings. Sections provide an overview of SERS biomedical applications, providing in-depth information about point-of-care and clinical applications of SERS using specific examples from current literature. These applications are not always immediately evident to newcomers in the field, as Raman and SERS are often introduced as analytical methods for chemical analysis. This book offers a concise introduction to the biomedical applications of SERS for graduate students, scientists and researchers in all related fields.

Part 1: Background 1. Label-free SERS in biomedical applications 2. SERS probes and labels for biomedical applications

Part 2: Point-of-Care applications 3. SERS biosensors for infectious disease diagnosis 4. SERS-based molecular sentinels for nucleic acid detection 5. Quantitative determination of cellular biomarker expression for identification of effective cancer treatments using SERS biosensors 6. Nanoporous gold substrates for SERS-based in vitro diagnostics

Part 3: (pre-)Clinical applications 7. SERS detection of oral and GI cancerous tissues 8. Surface-enhanced spatially offset Raman spectroscopy for breast cancer detection 9. Brain tumor delineation using gold nanostar SERS tags 10. Multiplexed cancer immunoimaging using SERS

Scientists, researchers, and graduate students using Surface-Enhanced Raman Spectroscopy (SERS) in the fields of chemistry, biology, biophotonics, nanotechnology, and physics who are interested applying SERS in clinical and point-of-care settings

• Highlights point-of-care applications for SERS
• Covers the recent biomedical applications of SERS carried out by leaders in the field
• Includes chapters on SERS probes and labels and label-free uses of SERS