Gene Delivery Nanotechnology and Therapeutic Applications Drugs and the Pharmaceutical Sciences Series

Gene delivery is a transport of genes of therapeutic values into the chromosomes of the cells or tissues which can be targeted to replace the faulty genes. In last two decades lot of research efforts are dedicated to gene delivery for therapeutic applications. Today gene therapy is promising approach in treatment of genetic diseases including mitochondrial related diseases like blindness, muscular dystrophy, cystic fibrosis, and some cancers.

Gene Delivery Systems: Nano Delivery Technologies observes the exploration of nanotechnology for gene therapy and gene delivery. Written by prominent authors in the field, this book covers various aspects of gene delivery including challenges in delivering gene therapy, advances in genome editing, RNA-based gene therapy, Green nanoparticles for oligonucleotide delivery.

Additional features include"

• Provides the most up to date information on the development of gene therapy, from the technology involved to gene correction and genome editing.
• Includes knowledge of the current application of CRISPR/Cas9 gene-editing technique; an approach that has recently been given the Noble Prize.
• Examines the development of mRNA vaccines for Covid -19 in challenging pandemic scenario
• Discusses siRNA, mRNA, and DNA plasmids.

Chapter 01

Challenges in delivering gene therapy

Chapter 02

Advances in genome editing: the technology of choice for precise and efficient disease treatment, with special focus on nano delivery systems

Chapter 03

Extracellular vesicles for nucleic acid delivery: progress and prospects for safe RNA-based gene therapy

Chapter 04

Green nanoparticles for oligonucleotide delivery

Chapter 05

Development of mRNA vaccines for Covid -19 in challenging Pandemic scenario

Chapter 06

Gene therapy for cardiovascular diseases: clinical evidences

Chapter 07

Current application of CRISPR/Cas9 gene-editing technique to eradication of HIV/AIDS

Chapter 08

siRNA delivery for therapeutic applications using nanoparticles

Chapter 09

Clinical perspectives on Gene therapy for retina and eye diseases

Chapter 10

Herpesvirus microRNAs for use in gene therapy immune-evasion strategies

Chapter 11

siRNA delivery for therapeutic applications using nanoparticles

Chapter 12

Gene therapy and small molecule treatment for cystic fibrosis

Chapter 13

CRISPR gene therapy recent trends and clinical applications

Chapter 14

Clinical applications of gene therapy for Immuno-deficiencies

Chapter 15

Regulatory challenges for nano gene delivery

Dr. Yashwant Pathak completed his Ph.D. in Pharmaceutical Technology from Nagpur University,

India and his EMBA MS in Conflict Management from Sullivan University. He is Professor and

Associate Dean for Faculty Affairs at the College of Pharmacy, University of South Florida. Tampa,

Florida. With extensive experience in academia as well as industry, he has more than 100 publications,

two patents and two patent applications, twenty edited books published, including seven books

in Nanotechnology and six in Nutraceuticals and drug delivery systems. He has several books in cultural

studies and conflict management. He has received several National and International awards.

His recent assignment was Fulbright Senior Fellow in Indonesia for six months, where he traveled

in seven countries and lectured in more than twenty universities. He was a key note speaker at the

World Hindu Wisdom meeting in Bali, Indonesia, in June 2017 and co-chaired with the Governor

of Bali. Dr Yashwant Pathak is also a Professor of Global Health with the College of Public Health

at USF. Recently, his student completed a PhD in Global Health on homeopathy medicine and its

efficacy, a survey of 1274 patients in Pune in India. Dr Pathak is also an adjunct faculty member at

AirLangga University College of Public Health at Surabaya Indonesia.