Epigenetics of Metabolism Translational Epigenetics Series

Epigenetics of Metabolism, a new volume in the Translational Epigenetics series, comprehensively explores epigenetic changes and the regulation of nutrient metabolism related to human development and disease. Here, international leaders in the field provide a broad overview of epigenetics in bodily and cellular metabolism, including epigenetic mechanisms involved in the metabolism of carbohydrates, proteins and lipids, as well as in related diseases. Also discussed are the roles of vitamins and minerals in epigenetics of metabolism, epigenetic changes in deficiency or toxicity of micronutrients, and the effects of natural plants, phytochemicals and intestinal bacteria.

This book offers researchers, students and health care practitioners a full grounding in nutrient-gene interactions in metabolism, with applied knowledge, research methods and protocols, and clinical pathways to drive new discovery and medical outcomes.

He graduated with a B.S. degree in cell biology from Lanzhou University and received both his M.S. and Ph.D. in Animal Nutrition from Virginia Tech where he studied protein metabolism. He completed his postdoctoral training in nutritional control of mammalian gene expression at the University of Florida, College of Medicine. Dr. Pan's research is to understand the adaptation of epigenetic modifications in mammalian gene regulation to the environment changes, with a focus on the impact of these adaptive processes in health and disease. Dr. Pan has over 65 peer-reviewed publications and receives grant support from the NIH, the United States Department of Agriculture, and industry.
The recipient of various NIH grants, Dr. Zheng’s current research projects include the discovery of the novel SUMOylation inhibitor as anti-influenza virus agent; the impact of Native American plants as therapeutic supplements on the prevention and treatment of hypertension, hyperlipidemia, and chronic inflammatory diseases; immunological consequences of transcription factor interactions; and the effects of maternal supplements on fetal developmental programing and offspring health outcomes. She has published in such peer reviewed journals as the Journal of Cellular Biochemistry, International Journal of Public Health Science, Journal of Nutrition and Food Sciences, Journal of Immunology, Molecular and Cell Biology, and Epigenetics.
Dr. Tollefsbol is a Distinguished Professor of Biology and a Senior Scientist in the O’Neal Comprehensive Cancer Center, Integrative Center for Aging Research, Nutrition Obesity Research Center, University Wide Microbiome Center, and the Comprehensive Diabetes Center at the University of Alabama at Birmingham (UAB). He is Director of the UAB Cell Senescence Culture Facility which he established in 1999. Dr. Tollefsbol trained as a Postdoctoral Fellow and Assistant Research Professor with members of the National Academy of Science at Duke University and the