Nano-Strategies for Addressing Antimicrobial Resistance, 1st ed. 2022 Nano-Diagnostics, Nano-Carriers, and Nano-Antimicrobials Nanotechnology in the Life Sciences Series

Antibiotics, the backbone of modern clinical-medicine, are facing serious challenges from emerging antimicrobial-resistance (AMR), a complicated phenomenon expanding in bacterial species, from nosocomial to community origins, where microbes are no longer sensitive to a range of commonly used antibiotics. AMR has exploded in recent years and is posing a serious threat to human health and survival. This necessitates novel and effective ways of diagnosis, drug-delivery, and treatment; nanotechnology and advanced nanomaterials are hailed as a potent solution in containing AMR.

The main thrust of this volume is to explain the most current research on the central theme of potential use of nano-approaches for diagnosis, detection, drug-delivery and as antimicrobial agents against drug-resistant pathogenic microbes. This book provides an integrated blend of basic and advanced information for students, scholars, scientists and practitioners, interested or already engaged in research in these areas. We have brought together leading international authors to present and highlight various aspects of nanotechnology in combating AMR in WHO-prioritized microbes. Topics range from advances in nanomaterial synthesis, characterization, functionalization and improvisation, as well as applications in sensing, diagnosis of AMR, and their therapeutic and drug-delivery potential against MDR and XDR microbial phenotypes.

1.The History of Antibiotics Illumes the Future of Antimicrobial Peptides Administered Through Nano-Systems.- 2.Current approaches and prospects of nanomaterials in rapid diagnosis of antimicrobial resistance.- 3.Nanomaterials-mediated delivery of antimicrobial agents ‘The Nanocarriers’.- 4.Nanoparticle functionalization: Approaches and applications.- 5.Nano-adjuvants as effective next-generation antimicrobial agents.- 6.Limiting antibiotic-resistant bacteria using multifunctional nanomaterials.- 7.Microbial resistance mechanisms and potential of metal-organic framework in mitigation thereof.- 8.Silver-based Nano-Formulations for Treating Antibiotic-Resistant Microbial Strains.- 9.Gold Nanoparticles: A Lethal Nanoweapon against Multidrug Resistant Bacteria.- 10.Antimicrobial Potentials of Zinc and Iron Oxide Nanoparticles.- 11.Carbon Nanostructures for Fighting Antimicrobial Resistant Bacteria.- 12.Nano-formulations against Multidrug Resistant Members of ESKAPE pathogens.

Dr. Vinay Kumar is working as an Associate Professor in Biotechnology Department, Modern College (Savitribai Phule Pune University), Ganeshkhind, Pune, India. He did his Ph.D. in Biotechnology from Savitribai Phule Pune University in 2009. He has published 70+ peer reviewed research/review articles with over 3400 citations, 27 book chapters besides editing 6 books. He is a recipient of Young Scientist Award from SERB, Government of India. His research interests include antimicrobial resistance (AMR) in community settings, elucidating mechanisms underlying AMR and combating it with phytochemicals and nanomaterials. He is on editorial and reviewer boards of reputed journals.  

Dr. Varsha Shriram has completed her PhD in natural products chemistry and biotechnology from CSIR-National Chemical Laboratory, Pune and Savitribai Phule Pune University, Pune, India. She is currently working as an Associate Professor, Botany Department, Prof.Ramkrishna More College, Akurdi (Savitribai Phule Pune University), Pune, India. She has published more than 35 peer-reviewed research/review articles, with over 2200 citations and is on reviewer board for reputed journals. Her areas of research interest include medicinal plants, phytochemicals, bioactivities including anticancer and antimicrobial resistance reversal. She has completed extramural research projects in these and allied areas.   

Dr. Ravi Shukla is currently an Associate Professor of Bioscience & Food Technology, and Co-leader of Sir Ian Potter Biosensing Facility, at the RMIT University Australia and routinely engages and contribute to day-to-day University academics. He has over 20 years of research experience in the interdisciplinary research areas spanning Biosciences, Food and Materials Science; and supervised 15 Ph.D., 5 Masters, and over 50 undergraduate researchers through to completion. His peers regard him as a meticulou